Propecia lasting sexual side effects

• A new study finds side effects of finasteride may continue months after stopping medication.
• 96% of subjects’ sexual problems lasted more than a year after stopping medication.
• Study authors believe finasteride may do permanent damage.

Food and Drug Administration (FDA) updated the warning to finasteride, Merck & Co.’s drug marketed to treat both male pattern baldness (Propecia) and enlarged prostate (Proscar). The new warnings noted that the sexual side effects associated with the medication, including problems with libido, ejaculations and orgasm, could last even after patients stop taking the drug.

Now a new study published in the Journal of Sexual Medicine finds that side effects may not only continue after stopping finasteride, but they may last for months or even years.

The FDA’s updated warning labels for finasteride were based on a review of post-marketing reports of sexual dysfunction. The agency reviewed 421 post-marketing reports of sexual side effects related to Propecia from 1998 to 2011; out of these cases, 59 reported adverse sexual effects lasting over three months after discontinuing the drug. For Proscar, the FDA reviewed 131 cases of erectile dysfunction and 68 cases of decreased libido from 1992 to 2010. As Healthland reported in April:

Finasteride labels will now warn users that Propecia’s side effects can include libido disorders, ejaculation disorders, and orgasm disorders that continue after discontinuation of the drug and that Proscar can lead to decreased libido that continues after quitting the drug. Both medications will receive a new description of reports of male infertility and poor semen quality that normalized or improved after stopping therapy.
“Despite the fact that clear causal links between finasteride (Propecia and Proscar) and sexual adverse events have not been established, the cases suggest a broader range of adverse effects than previously reported in patients taking these drugs,” the FDA said in a statement.